Nature Reviews Nephrology (2025)
https://www.nature.com/articles/s41581-025-01016-2
Abstract:
Approximately 480 million Indigenous peoples worldwide (about 6% of the global population) experience disproportionately high rates of chronic kidney disease (CKD). The legacy of colonialism—marked by poverty, systemic racism, and historical trauma—has created enduring health inequities. Geographic isolation, socioeconomic disadvantage, and discrimination limit access to preventive and culturally safe kidney care, resulting in delayed diagnosis, lower use of kidney replacement therapies, and higher mortality. Environmental and occupational exposures, along with inadequate infrastructure, further heighten CKD risk. Addressing these disparities requires culturally responsive, community-led health services, strengthened prevention and early detection programs, and policy reforms that recognize Indigenous sovereignty and knowledge systems. Promoting cultural safety and equity in kidney care is essential to improving health outcomes for Indigenous peoples globally.
Sources: WHO (2023); The Lancet Global Health (2022); ISN Kidney Health Equity Report (2023).